Indications:
Respiratory tract infections
Pelvic infections
Septicaemia
Gonorrhoea (non-penicillinase producing
strains)
Ear, nose and throat infections
Skin and soft tissue infections
Endocarditis
Syphilis
Dental abscess (as adjust to surgical
management)
Urinary tract infections
Meningitis
Gastro-intestinal infections
Orthopedic infections
Enteric fever
Prophylaxis of endocarditis
Contraindications:
Contraindicated in patients with history of previous hypersensitivity reaction
to any of penicillin or any component of the formulation.
Precautions: Pseudo-membranous
colitis has been reported with
nearly all-antibacterial agents,
and may range from mild to life
threaten. Therefore, it is important
to consider this diagnosis in
patients who present with diarrhea
subsequent to the administration
of antimicrobial agents. Super
infections with fungal or bacterial
pathogens should be kept in mind
during therapy.
Dosage:
Capsules:
Adults: 250-500 mg 6 to 8 hourly or more frequently according to severity
of the infections.
Syrup:
Adults: 250-500mg 6 to 8 hourly or more frequently according to severity
of the infections.
Children: 2 to 10 years : 125 to250 mg 6 to 8 hourly
Children: Upto 2 years : 75 to 150 mg 6 to 8 hourly
Administer: ½ to 1 hour before meals or as directed by the registered
physician
Paediatric Drop:
Paediatric drops are recommended for children under 6 month of age based
on body weight 35- 100 mg/kg/day ½ to 1 hour prior to feeding or as
directed by the registered physician.
Special dosage recommendations: Typhoid and para typhoid
Adults: 4 g daily in divided
doses for 14 to 21 days.
Children: 100 mg/kg/day in divided
doses for 14 to 21 days.
Typhoid Carrier
State 3 to 4 g daily in divided
doses
for minimum of one month.
Gonorrhoea: A single dose of 3 g plus 1
g probenecid where infection
is caused by penicillin sensitive
organisms
Meningitis: Adults: 150 mg/kg/day in equally
divided doses.
Syphilis: A dosage of 250 mg every 6 hours
has been used in all stages
of Syphilis. Duration of treatment
varied form 4 weeks upto 5
months according to the stage
of disease and serological
response.
Ottitis Media: In severe or recurrent ottitis
media, especially where compliance
may be a problem 750 mg twice
a day for 2 days may be used
in children of 3 to 10 years.
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