Dosage: Caps/Syp:Adt;250mg-1gm six hourly.Children:125-250mg six hourly
Precautions: Hepatic impairment
(monitor hepatic funcation,
pregnancy. Do not dilute
syp below halfstrenght. History
of allergy; renal impairment;
erythematous rashes common
in patients; erythematous
rashes common in glandular
fever, cytomegalovirus infection,
and acute or chronic lymphocytic
leukaemia. Streptococcal
infection; therapr must be
sufficient to eliminates
the organism (a minimum of
ten days) Otherwise the sequelae
of streptococcal disease
(endocarditis, rheumatic
fever) may occur. Avoid small
ineffective doses of penicillin
as resistant organisma are
more likerly to emerge. Serious
and occasionally fatal immediate
hypersensitivity (anaphylactoid)
reactions have been reported
AdverseEffects: Nausea, vomiting, diarrhoea,
rashes (discontinue treatment),
Rarely antibiotic-associated colitis.
Hypersensittivity reactions including
urticaria, fever, joint pains,
angioedema, anaphylaxis, serum
sickness-like reactions, haemolytic
anaemia and interstital nephritis
(e.g. oligouria, hematuria), neutropenia,
thrombocytopenia, coagulation disorders
and CNS toxicity including convulsions
Indication: Respiratory, ENT and softtissue
infection. UTI and gonorrhoea
ContraIndication: Pencillin hypersensitivity,
history of co-amoxiclav-associated
or penicillin associated jaundice
or hepatic dysfuncation
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