Description:
Ibuprofen (Macprofen) belongs to a group of medicines called non-steroidal anti-inflammatory drugs (or NSAIDs). It is an Anti-inflammatory, Anti-rheumatic, Analgesic and Anti-pyretic drug.

Indications:
Adults and Children 2-12 years: For fast & effective relief of headaches, toothache and menstrual pain, for minor aches and pain associated with arthritis, muscles, joints and backache, for reduction of fever and pain due to colds, sore throat, immunizatin and earache. Macprofen is also indicated in the treatment of the signs & symptoms of rheumatoid arthritis (including Juvenile arthritis or Still’s disease), ankylosing spondylitis, osteoarthritis, and other non- rheumatoid (seronegative) arthropathies and in non–articular rheumatic conditions. Ibuprofen (Macprofen) is indicated in the particular conditions such as frozen shoulder (capsulitis), bursitis, tendonitis, tenosynovitis and low back pain. Macprofen can also be used in soft tissue injuries such as sprains and strains.

Dosage and Administration:
Children under 2 years …5 mg/kg body weight.
Children over 2 years …10 mg/kg body weight
Note: Dose may be repeated every 6 to 8 hours while symptoms persist, up to three doses a day)

Macprofen Suspension in 3-4 times a day:
06 - 12 months 1/4 - 1/2 teaspoonful
12 - 24 months 1/2 - 1 teaspoonful
02 - 04 years 3/4 - 1 1/2 teaspoonful
04 - 08 years 1- 2 1/2 teaspoonful
08 - 12 years 1 1/2 -4 teaspoonful

Macprofen Tablets:
Adults…1200 mg daily in three divided doses.
In severe conditions, it can be advantageous to increase the dosage to 1600mg daily in divided doses until the acute phase is brought under control.
Dysmenorrheal…1200 mg per day in three divided doses; Analgesia…1200 to 1600 mg daily given in three divided doses.

Dental or post-operative pain an initial dose of 800 mg may be given.

Note: The total daily dose of Macprofen should not exceed 2400 mg.

Contraindications:
In common with other non-steroidal anti-inflammatory agents, Ibuprofen (Macprofen) should not be given to patients with severe or active peptic ulceration. Use during pregnancy, should be avoided, if possible.

Precautions:
Ibuprofen (Macprofen) should be prescribed with caution in patients with asthma especially in those who have developed bronchospasm using other non-steroidal agents.
Side-effects
Adverse reactions reported include dyspepsia, gastro-intestinal intolerance, bleeding and skin rashes. Thrombocytopenia and toxic amblyopia have occurred very rarely but in those cases reported, recovery occurred promptly on cessation of treatment.

Storage:
Store at room temperature. Protect from heat, light and moisture. Keep all medicine out of the reach of children.