Dosage: Adt: 75mg daily with or without food Non-ST segment elevation acute coronary syndrome: 300mg loading dose follwoed by 75mg daily given in combination with 75-100mg aspirin daily. Children:Not rec

Precautions: Renal impairment , moderate hapatic impairment, surgery risk of bleeding and blood dyscrasias; Perform blood counts promptly if suspected and when used with other drugs or conditions that affect bleeding. Warn patients to report unusual bleeding

AdverseEffects: Bleeding episodes, Gl upset, skin reactions Nervous system, hepatic billary or haematological disorders. Rarely, thrombotic thromboccytopeni purpura

Indication: Prevention of atherothrombolic events in patients suffering from myocardial in farction (from a few days until less than 35 days)ischaemic stroke (from day 7 until less than 8 months) or established peripheral artery disease in combination with aspirin in non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-Wave MI

ContraIndication: Severe hapatic impaiment , acute bleeding such as peptic ulcer or intracranial haeorrhage. Do not initiate therapy within first few days after MI. PTCA (stenting). CABG acute ischaemic stroke of less than 7 days. Pregnancy, lactation