Kaolin and pectin may be indicated as an adjunct to rest, fluids, and an appropriate diet in the symptomatic treatment of mild to moderately acute diarrhea. Use is recommended in chronic diarrhea only as temporary symptomatic treatment until the etiology is determined.

Mechanism of action/Effect:
Adsorbent and protectant. Kaolin is a natural hydrated aluminum silicate that is believed to adsorb large numbers of bacteria and toxins and reduce water loss. Pectin is a polyuronic polymer for which the mechanism of action is unknown. Pectin consists of purified carbohydrate extracted from citrus fruit or apple pomace. Studies have shown no decrease in stool frequency or fecal weight and water content with this combination even though stools appeared more formed.

Dosage:
Up to 1 year 5ml Every 3-4 Hours, 1 to 6 years 10ml Every 3-4 Hours, 6 to 12 years 15ml Every 3-4 Hours, 12 years and above 15ml Every 3-4 Hours (Or as advised by physician). Absorption: Not absorbed (up to 90% of pectin is decomposed in gastrointestinal tract).

Precautions to Consider Pregnancy/Reproduction:
Pregnancy—Problems in humans have not been documented. Kaolin and pectin combination is poorly absorbed after oral administration. Nursing Mother: Problems in humans have not been documented. Kaolin and pectin combination is poorly absorbed after oral administration.

Pediatrics:
In infants and children up to 3 years of age with diarrhea, use is not recommended unless directed by a physician because of the risk of fluid and electrolyte loss. Oral rehydration therapy is recommended in children with diarrhea to prevent loss of fluids and electrolytes.

Geriatrics:
In geriatric patients with diarrhea, caution is recommended because of the risk of fluid and electrolyte loss; these patients should be referred to a physician.

Drug interactions and/or related problems:
Oral medications, other (prolonged use of adsorbents may interfere with absorption of other oral agents administered concurrently; it is recommended that kaolin and pectin combination be administered at least 2 to 3 hours before or after other oral medications Constipation: usually mild and transient, but may rarely lead to fecal impaction Precautions while using this medication: Kaolin and pectin combination should not be used if diarrhea is accompanied by fever or if there is blood or mucus in the stool. Checking with physician if diarrhea is not controlled within 48 hours and/or fever develops Taking doses of other oral medications 2 to 3 hours before or after doses of kaolin and pectin combination.