Dosage: Manic depression psychosis: Adt and Children: Initially 400mg daily in divided doses increasing gradually in divided doses. usual renge, 400-600mg daily. Epilepsy: Adt: Initially 100-200mg once or twice daily increasing slowly to optimum dosage usually 800mg-1.2gm daily in divided doses. Max 1.6gm daily. Children: Up to 1 yr, 100-200mg; 1-5 yrs, 200-400mg; 5-10 yrs, 400-600mg; 10-15 yrs, 600mg-1gm. all daily in divided doses. Trigeminal neuralgia: Adt: Initially 100mg once or twice daily increasing gradully
to control, usually 600-800mg daily in divided doses; max. 1.6gm daily.
Children: Not applicable

Precautions: Pregnancy. Severe CVS disease. Hepatic or renal disorders. Elderly. Perform liver funcation tests and check blood count regularly

AdverseEffects: Gastric, Steroids, phenytoin, lithium mouth, drowsiness and dizziness. Oedema and rarely hyponatraemia. Blood dyscrasis, rashes, toxic epidermal necrolysis, hair loss. Acute renal failure lymph-node enlargement, cardiac conduction disturbances, hepatitis, and cholestatic jaundice

Indication: Prophylaxis of manic depression psychosis unresponsive to lithium. epilepsy: Generalised tonic clonic in divided pertial seizures. Trigmeinal neuralgia

ContraIndication: A-V conduction abnormalities unless paced. Lactation